Price per setting tells you the average rate you're paying. It doesn't tell you the rate for the extra capacity above what a cheaper machine already gives you — and that marginal rate is where a lot of "just get the bigger one" advice falls apart. Here's the same two machines, this time looking only at the gap between them:
($609.99 − $278.94) ÷ (8 − 6) = $165.53 per extra place setting
Stepping up from the COMFEE's 6 settings to the BLACK+DECKER's 8 costs $331.05 for two additional place settings — $165.53 for each one, more than double the BLACK+DECKER's own overall per-setting price of $76.25, and over three times the COMFEE's $46.49. That's the number that should give you pause: you are not paying the machine's average rate for those last two settings, you're paying a steep premium for them specifically.
Whether that premium is worth it depends on what else you're buying along with the two extra settings, because the BLACK+DECKER isn't just "a bigger COMFEE'." It's a different class of appliance entirely — a full 18-inch dishwasher on castors that rolls to the sink and gives you back a finished counter surface, versus a machine that permanently occupies close to two feet of worktop. If you specifically need the floor-standing class — more floor space than counter space, a household too big for six settings, or a long-term plan to convert the unit once you own a kitchen you can modify — the $165.53 marginal rate buys real, distinct value. If what you actually want is "the same machine, slightly bigger," the marginal math says don't: buy the cheaper machine twice before you'd spend the difference once.
Spread either price over the machine's working life and the marginal gap narrows further, which is really a question about ownership cost rather than sticker price — see how long a portable dishwasher actually lasts for how to think about that amortization honestly. And if the wheeled class appeals mainly because it feels like "the real appliance," it's worth knowing a handful of 18-inch models are designed to eventually install permanently — that's a different decision than the one in front of you today, covered in our guide to convertible portable dishwashers.